【基本信息】
姓 名:王颇
学历学位:博士研究生
职 称:教授
学科方向:分析化学,纳米材料
E-mail:wangpo@jsnu.edu.cn
【个人简介】
2011年,博士毕业后参加工作。2016年,入选江苏省“青蓝工程”优秀青年骨干教师。2018年,任职江苏师范大学ylzzcom永利总站线路检测副院长。2019年,入选江苏省“六大人才高峰”高层次人才。2022年,入选江苏省“333工程”中青年学术技术带头人。近年来,已主持国家自然科学基金面上项目、国家自然科学基金青年项目、江苏省重点研发计划、江苏省高层次人才项目、徐州市重点研发计划等项目12项;在Anal. Chem.,Chem. Commun.,ACS Sens.,Biosens. Bioelectron.,Langmuir,ACS Appl. Nano Mater.等期刊发表论文82篇,含ESI高被引论文2篇。已发表论文被他人引用3100余次,目前的H指数为33。研究成果先后荣获淮海科学技术奖、江苏省教育教学与研究成果奖、江苏省分析测试科学技术奖、徐州市“十大青年科技奖”等奖项。
【教育背景】
2014.02−2015.02:Florida International University(美国),化学系,博士后
2008.09−2011.06:中山大学,化学与化学工程学院,理学博士
2005.09−2008.06:安徽师范大学,ylzzcom永利总站线路检测,理学硕士
2001.09−2005.06:安徽师范大学,ylzzcom永利总站线路检测,理学学士
【工作经历】
2011.07−现在:江苏师范大学,ylzzcom永利总站线路检测,教师
【研究领域】
1. 生物电分析化学;
2. 核酸纳米技术;
3. 电化学界面构建与传感。
【研究项目与计划】
1. 国家自然科学基金面上项目,纸芯片电化学界面的构建及其在肿瘤抑制基因甲基化研究中的应用(21675067),65万元,2017.01−2020.12,主持。
2. 国家自然科学基金青年项目,p53肿瘤抑制基因突变状态的电化学识别及应用(21205052),25万元,2013.01−2015.12,主持。
3. 江苏省重点研发计划项目,肿瘤抑制基因的甲基化信息在纸芯片传感界面上的信号识别与医学应用(BE2019645),50万元,2019.07−2022.06,主持。
4. 江苏省“六大人才高峰”高层次人才计划项目,纸芯片纳米生物传感器的构建与应用(SWYY-084),4.0万元,2019.07−2022.06,主持。
5. 徐州市重点研发计划项目,DNA甲基化的电化学检测及其在恶性肿瘤早期诊断中的应用研究(KC19161),10万元,2019.08−2021.07,主持。
6. 江苏省“青蓝工程”优秀青年骨干教师培养计划,2.0万元,2016.05−2019.04,主持。
7. 江苏师范大学高层次人才队伍后备人选培养计划,10万元,2017.01−2020.12,主持。
8. 江苏省高校自然科学研究项目,肿瘤抑制基因突变状态的电化学检测及应用(12KJB150009),5.0万元,2012.09−2014.12,主持。
9. 江苏师范大学“153工程”人才培养项目,新型纳米电化学生物传感器的构建及应用(11XLR12),20万元,2012.01−2013.12,主持。
【部分学术论文】
[1] B. Dou, H. Zhou, X. Han, P. Wang*, Wedged DNA walker coupled with a bimetallic metal-organic framework electrocatalyst for rapid and sensitive monitoring of DNA methylation, Analytical Chemistry, 2023, 95, 994−1001.
[2] H. Shen, Z. Li, B. Dou*, Q. Feng, P. Wang*, An amplified logic gate driven by in situ synthesis of silver nanoclusters for identification of biomarkers, Chemical Communications, 2023, 59, 5705−5708.
[3] Q. Feng, L. Qin, B. Dou, X. Han, P. Wang*, Plasmon-tunable Ag@Au bimetallic core-shell nanostructures to enhance the electrochemiluminescence of quantum dots for microRNA sensing, ACS Applied Nano Materials, 2022, 5, 16325−16331.
[4] J. Chen, J. Yan, Q. Feng*, X. Miao, B. Dou, P. Wang*, Label-free and enzyme-free fluorescence detection of microRNA based on sulfydryl-functionalized carbon dots via target-initiated hemin/G-quadruplex-catalyzed oxidation, Biosensors and Bioelectronics, 2021, 176, 112955.350
[5] B. Dou, H. Zhou, Y. Hong, L. Zhao, P. Wang*, Cross-triggered and cascaded recycling amplification system for electrochemical detection of circulating microRNA in human serum, Chemical Communications, 2021, 57, 7116−7119.
[6] Q. Chen, T. Tian, E. Xiong, P. Wang*, X. Zhou*, CRISPR/Cas13a signal amplification linked immunosorbent assay for femtomolar protein detection, Analytical Chemistry, 2020, 92, 573−577.
[7] Q. Feng, L. Qin, M. Wang, P. Wang*, Signal-on electrochemical detection of DNA methylation based on the target-induced conformational change of a DNA probe and exonuclease III-assisted target recycling, Biosensors and Bioelectronics, 2020, 149, 111847.
[8] Q. Feng, M. Wang, X. Han, Q. Chen, B. Dou, P. Wang*, Construction of an electrochemical biosensing platform based on hierarchical mesoporous NiO@N-doped C microspheres coupled with catalytic hairpin assembly, ACS Applied Bio Materials, 2020, 3, 1276−1282.
[9] Q. Feng, M. Wang, L. Qin, P. Wang*, Dual-signal readout of DNA methylation status based on the assembly of a supersandwich electrochemical biosensor without enzymatic reaction, ACS Sensors, 2019, 4, 2615−2622.
[10] X. Miao, Z. Cheng, H. Ma, Z. Li, N. Xue, P. Wang*, Label-free platform for microRNA detection based on the fluorescence quenching of positively charged gold nanoparticles to silver nanoclusters, Analytical Chemistry, 2018, 90, 1098−1103. 350
[11] Q. Feng*, M. Wang, X. Zhao, P. Wang*, Construction of a cytosine-adjusted electrochemiluminescence resonance energy transfer system for microRNA detection, Langmuir, 2018, 34, 10153−10162.
[12] L. Qin, X. Han, Q. Feng*, P. Wang*, Construction of broom-like Ag@N,O-C sensing interface for electrochemical detection of circulating tumor DNA using entropy-driven DNA walker, Sensors and Actuators B: Chemical, 2023, 378, 133157.
[13] Y. Gao, Y. Fu, H. Li, Q. Feng, Y. Jiao*, B. Dou, P. Wang*, A disposable electrochemiluminescence biosensor sensitized with multipedal DNA walker for in situ quenching detection of DNA methylation, Sensors and Actuators B: Chemical, 2023, 394, 134323.
[14]T. Wu, C. Wang, X. Han, Q. Feng*, P. Wang*, Combination of DNA walker and Pb2+-specific DNAzyme-based signal amplification with a signal-off electrochemical DNA sensor for Staphylococcus aureus detection, Analytica Chimica Acta, 2022, 1222, 340179.
[15] S. Liu, Q. Li, H. Yang, P. Wang*, X. Miao, Q. Feng*, An in situ quenching electrochemiluminescence biosensor amplified with aptamer recognition-induced multi-DNA release for sensitive detection of pathogenic bacteria, Biosensors and Bioelectronics, 2022, 196, 113744.
[16]H. Zhou, H. Shen, B. Dou*, Q. Feng, X. Han, P. Wang*, Construction of a sensitive ratiometric electrochemical sensing platform for DNA methylation detection based on the design of multistep DNA amplification circuits, Sensors and Actuators B: Chemical, 2022, 370, 132491.
[17] X. Shan, Q. Feng, J. Yang*, P. Wang*, Dual-mode detection and efficient annihilation of pathogenic bacteria based on the construction of a ratiometric electrochemiluminescent/electrochemical sensor, Sensors and Actuators B: Chemical, 2022, 372, 132633.
[18] Q. Feng, L. Qin, P. Zhang, D. Li*, M. Liu, P. Wang*, Ratiometric electrochemical detection of microRNA based on construction of a hierarchical C@SnS2 nanoflower sensing interface, Chinese Journal of Analytical Chemistry, 2021, 49, e21020−e21028.
[19] J. Chen, J. Yan, B. Dou*, Q. Feng, X. Miao, P. Wang*, Aggregatable thiol-functionalized carbon dots-based fluorescence strategy for highly sensitive detection of glucose based on target-initiated catalytic oxidation, Sensors and Actuators B: Chemical, 2021, 330, 129325.
[20] H. Zhou, L. Zhao, Y. Hong, B. Dou*, P. Wang*, DNA triple helix complex-functionalized electrochemical sensor for sensitive detection of microRNA in human serum, Journal of The Electrochemical Society, 2021, 168, 057503.
[21] B. Dou, J. Yan, Q. Chen, X. Han*, Q. Feng, X. Miao, P. Wang*, Development of an innovative nitrite sensing platform based on the construction of carbon-layer-coated In2O3 porous tubes, Sensors and Actuators B: Chemical, 2021, 328, 129082.
[22] Y. Zhou, Y. Wang, S. Li, X. Fang, H. Yin*, P. Wang*, S. Ai, A novel photoelectrochemical immunosensor for N1-methyladenine detection based on BiVO4/g-C3N4 heterojunction with signal amplification of TiO2@NH2-MIL-125(Ti), Sensors and Actuators B: Chemical, 2020, 318, 128310.
[23] Q. Feng, X. Zhao, Y. Guo, M. Liu*, P. Wang*, Stochastic DNA walker for electrochemical biosensing sensitized with gold nanocages@graphene nanoribbons, Biosensors and Bioelectronics, 2018, 108, 97−102.
[24] Q. Feng, M. Wang, Q. Chen, P. Wang*, Direct electrochemical detection of guanosine-5′-monophosphate at choline monolayer supported and gold nanocages functionalized carbon nanotubes sensing interface, Sensors and Actuators B: Chemical, 2018, 274, 343−348.
[25] H. Wang, L. Zhu, J. Duan, M. Wang, H. Yin*, P. Wang*, S. Ai, Photoelectrochemical biosensor for HEN1 RNA methyltransferase detection using peroxidase mimics PtCu NFs and poly(U) polymerase-mediated RNA extension, Biosensors and Bioelectronics, 2018, 103, 32−38.
[26] C. Sui, Y. Zhou, M. Wang, H. Yin*, P. Wang*, S. Ai, Aptamer-based photoelectrochemical biosensor for antibiotic detection using ferrocene modified DNA as both aptamer and electron donor, Sensors and Actuators B: Chemical, 2018, 266, 514−521.
[27] P. Wang*, Z. Cheng, Q. Chen, L. Qu, X. Miao, Q. Feng, Construction of a paper-based electrochemical biosensing platform for rapid and accurate detection of adenosine triphosphate (ATP), Sensors and Actuators B: Chemical, 2018, 256, 931−937.
[28] P. Wang*, M. Wang, F. Zhou, G. Yang, L. Qu, X. Miao, Development of a paper-based, inexpensive, and disposable electrochemical sensing platform for nitrite detection, Electrochemistry Communications, 2017, 81, 74−78.
[29] F. Zhou, Y. Yao, J. Luo, X. Zhang, Y. Zhang, D. Yin, F. Gao*, P. Wang*, Proximity hybridization-regulated catalytic DNA hairpin assembly for electrochemical immunoassay based on in situ DNA template-synthesized Pd nanoparticles, Analytica Chimica Acta, 2017, 969, 8−17.
[30] F. Gao, F. Zhou, Y. Yao, Y. Zhang, L. Du, D. Geng*, P. Wang*, Ordered assembly of platinum nanoparticles on carbon nanocubes and their application in the non-enzymatic sensing of glucose, Journal of Electroanalytical Chemistry, 2017, 803, 165−172.
[31] F. Gao, F. Zhou, S. Chen, Y. Yao, J. Wu, D. Yin, D. Geng*, P. Wang*, Proximity hybridization triggered rolling-circle amplification for sensitive electrochemical homogeneous immunoassay, Analyst, 2017, 142, 4308−4316.
[32] X. Miao*, Z. Cheng, Z. Li, P. Wang*, A novel sensing platform for sensitive cholesterol detection by using positively charged gold nanoparticles, Biochemical Engineering Journal, 2017, 117, 21−27.
[33] P. Wang*, C. Han, F. Zhou, J. Lu*, X. Han, Z. Wang, Electrochemical determination of tert-butylhydroquinone and butylated hydroxyanisole at choline functionalized film supported graphene interface, Sensors and Actuators B: Chemical, 2016, 224, 885−891.
[34]P. Wang*, F. Zhou, Z. Wang, C. Lai*, X. Han, Substrate-induced assembly of PtAu alloy nanostructures at choline functionalized monolayer interface for nitrite sensing, Journal of Electroanalytical Chemistry, 2015, 750, 36−42.
[35] P. Wang*, P. Han, L. Dong, X. Miao, Direct potential resolution and simultaneous detection of cytosine and 5-methylcytosine based on the construction of polypyrrole functionalized graphene nanowall interface, Electrochemistry Communications, 2015, 61, 36−39.
[36] P. Wang*, X. Li, Z. Dai*, X. Zou, X. Han, An efficient electrochemical method for direct screening of the mutation status of DNA base in oligonucleotides, Sensors and Actuators B: Chemical, 2014, 201, 222−227.
[37] P. Wang*, H. Chen, J. Tian, Z. Dai, X. Zou*, Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases, Biosensors and Bioelectronics, 2013, 45, 34−39.
[38] P. Wang, H. Wu, Z. Dai*, X. Zou*, Picomolar level profiling of the methylation status of the p53 tumor suppressor gene by a label-free electrochemical biosensor, Chemical Communications, 2012, 48, 10754−10756.
[39] P. Wang, H. Wu, Z. Dai*, X. Zou*, Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film, Biosensors and Bioelectronics, 2011, 26, 3339−3345.
[40] P. Wang, Z. Mai, Z. Dai*, X. Zou*, Investigation of DNA methylation by direct electrocatalytic oxidation, Chemical Communications, 2010, 46, 7781−7783.350
【获奖情况】
1. 2022年01月,江苏省“333工程”中青年学术技术带头人
2. 2019年07月,江苏省“六大人才高峰”高层次人才
3. 2016年05月,江苏省“青蓝工程”优秀青年骨干教师
4. 2018年08月,徐州市“十大青年科技奖”
5. 2018年08月,江苏省“教育教学与研究成果奖”
6. 2020年05月,徐州市“青年科技人才先锋岗”
7. 2018年09月,淮海科学技术奖,一等奖
8. 2018年11月,江苏省分析测试科学技术奖,二等奖
9. 2018年12月,徐州市发明协会科学技术“突出贡献奖”
10. 2023年01月,江苏师范大学“青年英才苗圃计划”
11. 2022年12月,江苏师范大学民族学生“曙光导师”
12. 2018年09月,江苏师范大学“三全育人”先进个人
13. 2017年06月,江苏师范大学“优秀指导教师”
14. 2016年05月,江苏师范大学“优秀共产党员”
15. 2015年12月,江苏师范大学“教学评优赛”,二等奖
16. 2011年12月,中山大学“芙兰论文奖”
17. 2010年12月,中山大学“优秀研究生”,一等奖
18. 2010年11月,中山大学“优秀论文奖”
19. 2010年06月,广东光华奖,一等奖
20. 2009年12月,省级优秀硕士学位论文
21. 2008年04月,省级“品学兼优毕业研究生”
【指导学生情况】
1. 2020年12月,指导黄云同学获得“国家奖学金”
2. 2020年09月,指导周慧同学获得“省级研究生科研与实践创新计划”项目
3. 2020年06月,指导黄云同学获得“朱敬文奖学金”
4. 2019年06月,指导赵晓蕾同学获得“优秀学位论文”
5. 2018年12月,指导刘硕同学参加“江苏省师范生教学基本功大赛”,获一等奖
6. 2018年05月,指导赵晓蕾同学获得“朱敬文特别奖学金”
7. 2018年05月,指导赵晓蕾同学获得“省级三好学生”
8. 2018年03月,指导赵晓蕾同学获得“科技创新奖”
9. 2017年12月,指导董景娇同学参加“江苏省师范生教学基本功大赛”,获一等奖
10. 2017年11月,指导赵晓蕾同学获得“国家奖学金”
11. 2017年07月,指导殷玉杰同学参加“全国高等师范院校化学实验邀请赛”,获二等奖
12. 2017年06月,指导董亮同学获得“优秀学位论文”
13. 2016年05月,指导2013级化学(师范)班(13化11)获得“省级先进班集体”
14. 2016年05月,指导董亮同学获得“省级三好学生”
15. 2015年11月,指导杨靓同学参加“江苏省师范生教学基本功大赛”,获一等奖
16. 2015年11月,指导李薇同学参加“江苏省师范生教学基本功大赛”,获二等奖
17. 2015年09月,指导董亮同学获得“国家奖学金”
18. 2015年07月,指导江晓莉同学参加“全国高等师范院校化学实验邀请赛”,获一等奖
19. 2015年07月,指导樊金晓同学参加“全国高等师范院校化学实验邀请赛”,获一等奖
20. 2015年07月,指导薛春慧同学参加“全国高等师范院校化学实验邀请赛”,获二等奖
21. 2015年05月,指导韩萍、董亮同学获得国家级“大学生创新创业训练计划项目”
【招生与交流】
1. 招收“化学”和“材料科学与工程”专业的研究生;
2. 欢迎国内外专家、学者来课题组指导、交流、合作。