报告人: 张晓兵 博士
湖南大学ylzzcom永利总站线路检测教授、博士生导师
国家杰出青年科学基金获得者
报告题目:新型有机小分子和功能核酸荧光探针
报告时间:
报告地点:化学ylzzcom永利总站线路检测二楼学术报告厅211
主办单位:化学ylzzcom永利总站线路检测、科技处
1998年于湖南大学获有机化学硕士学位。2001年获分析化学博士学位并留校任教。2003-05年在法国里昂高等师范学校、瑞典皇家工学院从事生物有机化学方向博士后研究,2005年3月加入化学生物传感与计量学国家重点实验室,2006年起任教授。分别于2008年6-9月以邀请教授的身份到法国里昂高等师范学校,2009年2-8月以高级访问学者的身份到美国伊利诺伊大学香槟分校从事生物分析领域的科研合作。曾获2001年湖南省科技进步二等奖,2004年湖南省优秀博士学位论文及全国优秀博士学位论文提名,2008年教育部自然科学一等奖及2008年中国专利优秀奖。近5年发表通讯作者SCI源刊论文58篇,单篇最高他引132次,其中影响因子>5.0的论文37篇,包括J. Am. Chem. Soc. 3篇,Angew. Chem. Int. Ed. 3篇,Anal. Chem. 15篇,Chem. Commun. 4篇等。曾主持国家自然科学基金项目4项,国家“
代表性论文:
1. Zilong Zhao, Hongmin Meng, Nannan Wang, Michael J. Donovan, Ting Fu, Mingxu You, Xiao-Bing Zhang,* and Weihong Tan,* A Controlled-release Nanocarrier with pHe-driven Targeting and Translocation for Drug Delivery, Angew. Chem. Int. Ed. 2013, 52, 7487-7491.
2. Tao Chen, Cuichen Sam Wu, Elizabeth Jimenez, Zhi Zhu, Joshua G. Dajac, Mingxu You, Da Han, Xiao-Bing Zhang,* and Weihong Tan,* DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy, Angew. Chem. Int. Ed. 2013, 52, 2012-2016.
3. Mingxu You, Yan Chen, Xiao-Bing Zhang,* Haipeng Liu, Ruowen Wang, Kelong Wang, Kathryn R. Williams, WeihongTan,* An Autonomous and Controllable Light-Driven DNA Walking Device, Angew. Chem. Int. Ed. 2012, 51, 2457-2460.
4. Tao Chen, Ismail Oecsoy, Quan Yuan, Ruowen Wang, Mingxu You, Zilong Zhao, Erqun Song, Xiao-Bing Zhang,* and Weihong Tan,* One-Step Facile Surface Engineering of Hydrophobic Nanocrystals with Designer Molecular Recognition, J. Am. Chem. Soc. 2012, 134, 13164-13167.
5. Liu Yang, Ling Meng, Xiao-Bing Zhang,* Yan Chen, Guizhi Zhu, Haipeng Liu, Kwame Sefah, and Weihong Tan,* Engineering Polymeric Aptamers for Selective Cytotoxicity. J. Am. Chem. Soc. 2011, 133, 13380-13386.
6. Li-Min Lu, Xiao-Bing Zhang,* Rong-Mei Kong, Bin Yang, and Weihong Tan,* Ligation-triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal. J. Am. Chem. Soc. 2011, 133, 11686-11691.
7. Yi-Jun Gong, Xiao-Bing Zhang,* Cui-Cui Zhang, Ai-Li Luo, Weihong Tan, Guo-Li Shen, and Ru-Qin Yu, Through Bond Energy Transfer: A Convenient and Universal Strategy towards Efficient Ratiometric Fluorescent Probe for Bio-imaging Applications. Anal. Chem. 2012, 84, 10777-10784.
8. Rong-Mei Kong, Xiao-Bing Zhang,* Zhuo Chen, Hong-Min Meng, Zhi-Ling Song, Weihong Tan, Guo-Li Shen, and Ru-Qin Yu, A Unimolecular Catalytic DNA Biosensor for Amplified Detection of L-Histidine via an Enzymatic Recycling Cleavage Strategy, Anal. Chem. 2011, 83, 7603-7606.
9. Xiao-Bing Zhang,* Zi-Dong Wang, Hang Xing, Yu Xiang, and Yi Lu. Catalytic and molecular beacons for amplified detection of metal ions and organic molecules with high sensitivity. Anal. Chem. 2010, 82, 5005-5011.
10. Yan Zhao, Xiao-Bing Zhang,* Zhi-Xiang Han, Li Qiao, Chun-Yan Li, Lixin Jian, Guo-Li Shen and Ru-Qin Yu, A Highly Sensitive and Selective Colorimetric and OFF-ON Fluorescent Chemosensor for Cu2+ in Aqueous Solution and Living Cells. Anal. Chem. 2009, 81, 7022-7030.